Seung-Yong Yoon on When Autophagy Stops, Microglia Sour into Senescence
COMMENT In this paper, inhibition of microglial autophagy induced senescence, suppressed disease-associated microglia, impaired engagement with Aβ plaques, and aggravated neuropathology. The senolytic drugs dasatinib and quercetin removed senescent microglia, res